Our study, through the integration of transcriptomic data and single-cell paired BCR profiles, revealed BCR repertoire changes in COVID-19 patients with severe illness, which is consistent with other studies focusing on subjects infected and/or vaccinated against SARS-CoV-2 subjects [29]

Our study, through the integration of transcriptomic data and single-cell paired BCR profiles, revealed BCR repertoire changes in COVID-19 patients with severe illness, which is consistent with other studies focusing on subjects infected and/or vaccinated against SARS-CoV-2 subjects [29]. ==

Vaccine tests in immunocompromised hosts should be encouraged to assess antibody assays associated with clinical protection as well as indirect measures such as functional and complete type-specific antibody levels

Vaccine tests in immunocompromised hosts should be encouraged to assess antibody assays associated with clinical protection as well as indirect measures such as functional and complete type-specific antibody levels. using both functional antibody assays and standard ELISA antibody titers. (ClinicalTrials.gov:NCT00307125)